Issue 105, 2014
From the journal:

RSC Advances

3D nanostructural analysis of silk fibroin and recombinant spidroin 1 scaffolds by scanning probe nanotomography†

Anton E. Efimov,*ab   Mikhail M. Moisenovich,c   Vladimir G. Bogushd  and  Igor I. Agapov*a  

* Corresponding authors

a Laboratory of Bionanotechnology, V.I.Shumakov Federal Research Center of Transplantology and Artificial Organs, Shchukinskaya str., 1, Moscow, Russia
E-mail: antefimov@gmail.com, igor_agapov@mail.ru
Tel: +7 4991906619

b SNOTRA LLC., Shcherbakovskaya str., 3, Moscow, Russia
Tel: +7 9161642475

c Faculty of Biology, Moscow State University, Leninskiye Gory 1, Building 12, Moscow 119991, Russia
E-mail: mmoisenovich@mail.ru
Tel: +7 4959395738

d Laboratory for Protein Engineering, The State Scientific Center of Russian Federation “The State Research Institute for Genetics and Selection of Industrial Microorganisms”, 1st Dorozhny, 1, Moscow, Russia
E-mail: vlbogush@mail.ru
Fax: +7 4953150501
Tel: +7 4953153747

Abstract

We use serial section scanning probe nanotomography to study the 3D structure, nanoporosity and pore interconnectivity of biocompatible scaffolds made of fibroin and recombinant spidroin 1 (rS1/9). Significant nanoporosity (24%) and pore percolation is detected for rS1/9 scaffolds. It is assumed to contribute to higher in vivo tissue regeneration efficiency of rS1/9 scaffolds.

Graphical abstract: 3D nanostructural analysis of silk fibroin and recombinant spidroin 1 scaffolds by scanning probe nanotomography

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Article information

DOI
https://doi.org/10.1039/C4RA08341E
Article type
Communication
Submitted
08 Aug 2014
Accepted
10 Nov 2014
First published
10 Nov 2014

RSC Adv., 2014,4, 60943-60947

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3D nanostructural analysis of silk fibroin and recombinant spidroin 1 scaffolds by scanning probe nanotomography

A. E. Efimov, M. M. Moisenovich, V. G. Bogush and I. I. Agapov, RSC Adv., 2014, 4, 60943 DOI: 10.1039/C4RA08341E

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