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Issue 93, 2014
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Development of a prokaryotic-like polycistronic expression system based on a virus-originated internal ribosome entry site (IRES) in industrial eukaryotic microorganisms

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Abstract

A prokaryotic-like polycistronic expression system was developed in Pichia pastoris and Acremonium chrysogenum. With simplicity and higher effectiveness, this polycistronic expression system is suitable for introducing multiple genes or entire metabolic pathways into industrial eukaryotic microorganisms.

Graphical abstract: Development of a prokaryotic-like polycistronic expression system based on a virus-originated internal ribosome entry site (IRES) in industrial eukaryotic microorganisms

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Article information


Submitted
27 Jul 2014
Accepted
07 Oct 2014
First published
07 Oct 2014

RSC Adv., 2014,4, 51615-51618
Article type
Communication
Author version available

Development of a prokaryotic-like polycistronic expression system based on a virus-originated internal ribosome entry site (IRES) in industrial eukaryotic microorganisms

L. Xu, G. Wang, W. Wang, X. Lv, Q. Li and A. Yan, RSC Adv., 2014, 4, 51615
DOI: 10.1039/C4RA07679F

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