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Issue 68, 2014
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Access to 6-arylpyrrolo[2,3-d]pyrimidines via a palladium-catalyzed direct C–H arylation reaction

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Abstract

An efficient method of palladium-catalyzed direct arylation has been developed for the selective functionalization of the C6 position of 2,4-diarylpyrrolo[2,3-d]pyrimidines. Under optimal conditions, various aryl bromides successfully provided a wide range of 6-arylpyrrolo[2,3-d]pyrimidines.

Graphical abstract: Access to 6-arylpyrrolo[2,3-d]pyrimidines via a palladium-catalyzed direct C–H arylation reaction

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The article was received on 17 Jun 2014, accepted on 29 Jul 2014 and first published on 29 Jul 2014


Article type: Paper
DOI: 10.1039/C4RA07088G
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Citation: RSC Adv., 2014,4, 35966-35974

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    Access to 6-arylpyrrolo[2,3-d]pyrimidines via a palladium-catalyzed direct C–H arylation reaction

    J. Dodonova and S. Tumkevicius, RSC Adv., 2014, 4, 35966
    DOI: 10.1039/C4RA07088G

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