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Issue 68, 2014
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Access to 6-arylpyrrolo[2,3-d]pyrimidines via a palladium-catalyzed direct C–H arylation reaction

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Abstract

An efficient method of palladium-catalyzed direct arylation has been developed for the selective functionalization of the C6 position of 2,4-diarylpyrrolo[2,3-d]pyrimidines. Under optimal conditions, various aryl bromides successfully provided a wide range of 6-arylpyrrolo[2,3-d]pyrimidines.

Graphical abstract: Access to 6-arylpyrrolo[2,3-d]pyrimidines via a palladium-catalyzed direct C–H arylation reaction

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Supplementary files

Article information


Submitted
17 Jun 2014
Accepted
29 Jul 2014
First published
29 Jul 2014

RSC Adv., 2014,4, 35966-35974
Article type
Paper
Author version available

Access to 6-arylpyrrolo[2,3-d]pyrimidines via a palladium-catalyzed direct C–H arylation reaction

J. Dodonova and S. Tumkevicius, RSC Adv., 2014, 4, 35966
DOI: 10.1039/C4RA07088G

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