Issue 89, 2014
From the journal:

RSC Advances

Asymmetric synthesis towards doxanthrine, a dopamine D1 full agonist†

Rajesh Malhotra,a   Amit Ghosh,ab   Swarup Dutta,b   Tushar K. Dey,ab   Sourav Basu*b  and  Saumen Hajra*cd  

* Corresponding authors

a Department of Chemistry, Guru Jambheshwar University of Science and Technology, Hisar, Haryana 125001, India

b TCG Life Sciences Ltd, Saltlake, Kolkata 700091, India
E-mail: sourav@chembiotek.com
Fax: +91-33-23673058
Tel: +91-33-23673151

c Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur 721302, India
E-mail: shajra@chem.iitkgp.ernet.in
Fax: +91-3222-282252
Tel: +91-3222-283340

d Centre of Biomedical Research, SGPGIMS Campus, Lucknow 226014, India
E-mail: saumen.hajra@cbmr.res.in

Abstract

Asymmetric synthesis of O-methyl doxanthrine is accomplished with high diastereo- and enantioselectivity from β-aryloxyamino acid derived from D-serine.

Graphical abstract: Asymmetric synthesis towards doxanthrine, a dopamine D1 full agonist

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Article information

DOI
https://doi.org/10.1039/C4RA06617K
Article type
Communication
Submitted
03 Jul 2014
Accepted
23 Sep 2014
First published
24 Sep 2014

RSC Adv., 2014,4, 48344-48347

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Asymmetric synthesis towards doxanthrine, a dopamine D1 full agonist

R. Malhotra, A. Ghosh, S. Dutta, T. K. Dey, S. Basu and S. Hajra, RSC Adv., 2014, 4, 48344 DOI: 10.1039/C4RA06617K

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