Issue 65, 2014
From the journal:

RSC Advances

FRET based ‘red-switch’ for Al3+ over ESIPT based ‘green-switch’ for Zn2+: dual channel detection with live-cell imaging on a dyad platform†

Shyamaprosad Goswami,*a   Abhishek Manna,a   Sima Paul,a   Anup Kumar Maity,b   Partha Saha,b   Ching Kheng Quahc  and  Hoong-Kun Funcd  

* Corresponding authors

a Department of Chemistry, Indian Institute of Engineering Science & Technology, Shibpur, West Bengal, India
E-mail: spgoswamical@yahoo.com

b Crystallography and Molecular Biology Division, Saha Institute of Nuclear Physics, West Bengal, India

c X-ray Crystallography Unit, School of Physics, Universiti Sains Malaysia, Penang, Malaysia

d Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia

Abstract

Our designed chemosensor, rhodamine-HBT-dyad (RHD), selectively detects two biologically important ions (Al3+ and Zn2+) at two different wavelengths (‘naked-eye’ colors red and green, respectively) through two different mechanisms (i.e. FRET and ESIPT) at ppm level. The sensor can also detect the Al3+ ion through displacement of the Zn2+ ion in vivo.

Graphical abstract: FRET based ‘red-switch’ for Al3+ over ESIPT based ‘green-switch’ for Zn2+: dual channel detection with live-cell imaging on a dyad platform

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Article information

DOI
https://doi.org/10.1039/C4RA05714G
Article type
Communication
Submitted
20 Mar 2014
Accepted
24 Jul 2014
First published
24 Jul 2014

RSC Adv., 2014,4, 34572-34576

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FRET based ‘red-switch’ for Al3+ over ESIPT based ‘green-switch’ for Zn2+: dual channel detection with live-cell imaging on a dyad platform

S. Goswami, A. Manna, S. Paul, A. K. Maity, P. Saha, C. K. Quah and H. Fun, RSC Adv., 2014, 4, 34572 DOI: 10.1039/C4RA05714G

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