Green synthesis of gold nanoparticles using aqueous Aegle marmelos leaf extract and their application for thiamine detection

Abstract

Nanoparticles of noble metals, especially gold nanoparticles are studied extensively because of their new and amazing properties. Among several synthesis techniques, green synthesis of nanoparticles is promising in recent years. In this study, we investigated the potential of Aegle marmelos leaf extract (LE) in reduction of HAuCl₄ to form ∼38.2 ± 10.5 nm spherical shape polyphenol capped gold nanoparticles. The stoichiometric proportion of the LE to HAuCl₄ and the equilibrium time to complete the reduction process for the nanoparticle formation were also identified. The total reaction time was observed to be within ∼30 min from the particle formation kinetics study. The as-synthesized gold nanoparticles capped with polyphenols of leaf extract were shown to be very effective for the detection of vitamin B or thiamine to a minimum concentration of ∼0.5 μM.