Issue 42, 2014
From the journal:

RSC Advances

Surface group mediates the adsorption of in situ generated thrombin and its interaction with anti-thrombin in the protein corona of SBA-15†

Yunlong Li,a   Xiaofeng Liao,a   Pu Liu,b   Xiaoqiang Shang,a   Guicen Ma,a   Hao Chena  and  Jie Fan*a  

* Corresponding authors

a Key Lab of Applied Chemistry of Zhejiang Province, Department of Chemistry, Zhejiang University, Hangzhou, China
E-mail: jfan@zju.edu.cn
Fax: +86 571 87952338
Tel: +86 571 87952338

b School of Basic Medical Sciences, Zhejiang University, Hangzhou 310058, China

Abstract

The surface groups of mesoporous silica (MPS) play an important role in mediating the hard protein corona (HPC) formation on its surface, leading to bio-identities with completely different procoagulant activities.

Graphical abstract: Surface group mediates the adsorption of in situ generated thrombin and its interaction with anti-thrombin in the protein corona of SBA-15

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Article information

DOI
https://doi.org/10.1039/C4RA02106A
Article type
Communication
Submitted
11 Mar 2014
Accepted
28 Apr 2014
First published
29 Apr 2014

RSC Adv., 2014,4, 21753-21756

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Surface group mediates the adsorption of in situ generated thrombin and its interaction with anti-thrombin in the protein corona of SBA-15

Y. Li, X. Liao, P. Liu, X. Shang, G. Ma, H. Chen and J. Fan, RSC Adv., 2014, 4, 21753 DOI: 10.1039/C4RA02106A

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