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Issue 13, 2014
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A highly sensitive and selective turn-on fluorescent chemodosimeter for Cu2+ based on BODIPY and its application in bioimaging

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Abstract

A BODIPY-based turn-on fluorescent probe 1 has been designed and synthesized for fluorescence detection of Cu2+ in aqueous media and imaging in living cells. The C[double bond, length as m-dash]N bonds are selectively hydrolyzed by the reaction with Cu2+ to generate formyl-BODIPY. The favorable features of probe 1 towards Cu2+ include significant fluorescence enhancement (over 290-fold), high selectivity and low detection limit (0.1 μM).

Graphical abstract: A highly sensitive and selective turn-on fluorescent chemodosimeter for Cu2+ based on BODIPY and its application in bioimaging

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Supplementary files

Article information


Submitted
29 Nov 2013
Accepted
02 Jan 2014
First published
06 Jan 2014

RSC Adv., 2014,4, 6691-6695
Article type
Communication

A highly sensitive and selective turn-on fluorescent chemodosimeter for Cu2+ based on BODIPY and its application in bioimaging

J. Ye, J. Xu, H. Chen, Y. Bai, W. Zhang and W. He, RSC Adv., 2014, 4, 6691
DOI: 10.1039/C3RA47157H

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