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Issue 15, 2014
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Synthesis of a dextran-based bone tracer for in vivo magnetic resonance and optical imaging by two orthogonal coupling reactions

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Abstract

Synthesis of dextran-based bone tracers for in vivo imaging from a dextran-template containing terminal acetylenes and amino groups though a diethylene glycol spacer is described. The tracer was used to visualize regenerated bone in a BMP-2 installed hydrogel by magnetic resonance and optical imaging.

Graphical abstract: Synthesis of a dextran-based bone tracer for in vivo magnetic resonance and optical imaging by two orthogonal coupling reactions

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Publication details

The article was received on 26 Oct 2013, accepted on 13 Nov 2013 and first published on 14 Nov 2013


Article type: Communication
DOI: 10.1039/C3RA46142D
RSC Adv., 2014,4, 7561-7565

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    Synthesis of a dextran-based bone tracer for in vivo magnetic resonance and optical imaging by two orthogonal coupling reactions

    H. Tanaka, S. Yamaguchi, J. Jo, I. Aoki, Y. Tabata and T. Takahashi, RSC Adv., 2014, 4, 7561
    DOI: 10.1039/C3RA46142D

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