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Issue 1, 2014
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An efficient green chemistry protocol for the synthesis of novel spiropyrrolizidine compounds

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Abstract

An efficient method for the synthesis of spirooxindolopyrrolizidine/spirooxindolothiapyrrolizidine by the 1,3-dipolar cycloaddition of azomethine ylides generated via, decarboxylative condensation of 1,2-dicarbonyl compounds and L-proline/L-thiaproline/sarcosine with chalcones at ambient conditions with excellent yields has been described.

Graphical abstract: An efficient green chemistry protocol for the synthesis of novel spiropyrrolizidine compounds

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Supplementary files

Article information


Submitted
23 Aug 2013
Accepted
06 Nov 2013
First published
07 Nov 2013

RSC Adv., 2014,4, 279-285
Article type
Paper

An efficient green chemistry protocol for the synthesis of novel spiropyrrolizidine compounds

K. Revathy and A. Lalitha, RSC Adv., 2014, 4, 279
DOI: 10.1039/C3RA44627A

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