Issue 45, 2013

Antimicrobial activity of non-natural prodigiosenes

Abstract

Tripyrrolic prodigiosenes, derivatives of the natural product prodigiosin, have been produced via multi-step synthesis beginning with 2-formyl pyrroles bearing various functionalities at the 4-position. Two tin complexes are also reported, and these feature a prodigiosene ligand bearing a conjugated benzyl-ester. Antimicrobial activities of prodigiosenes are evaluated against Gram positive and Gram negative bacterial strains, as well as a yeast.

Graphical abstract: Antimicrobial activity of non-natural prodigiosenes

Supplementary files

Article information

Article type
Communication
Submitted
09 Sep 2013
Accepted
04 Oct 2013
First published
18 Oct 2013

RSC Adv., 2013,3, 22967-22971

Antimicrobial activity of non-natural prodigiosenes

E. Marchal, Md. I. Uddin, D. A. Smithen, C. L. A. Hawco, M. Lanteigne, D. P. Overy, R. G. Kerr and A. Thompson, RSC Adv., 2013, 3, 22967 DOI: 10.1039/C3RA45479G

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