The first stereoselective total synthesis of the Z-isomer of (6S,7R,9R)-6,7-dihydroxy-9-propylnon-4-eno-9-lactone†
Abstract
The first stereoselective total synthesis of the Z-isomer of (6S,7R,9R)-6,7-dihydroxy-9-propylnon-4-eno-9-lactone involving Sharpless titanium(IV) mediated regioselective ring-opening reaction, Steglich esterification and RCM as the key steps is reported.