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Issue 40, 2013

One-pot fluorination and asymmetric Michael addition promoted by recyclable fluorous organocatalysts

Author affiliations

Abstract

A novel one-pot fluorination and asymmetric Michael addition reaction sequence promoted by recyclable fluorous bifunctional cinchona alkaloid–thiourea organocatalysts is introduced for the synthesis of α-fluoro-β-ketoesters bearing two chiral centers.

Graphical abstract: One-pot fluorination and asymmetric Michael addition promoted by recyclable fluorous organocatalysts

Supplementary files

Article information


Submitted
21 May 2013
Accepted
26 Jul 2013
First published
30 Jul 2013

RSC Adv., 2013,3, 18267-18270
Article type
Communication

One-pot fluorination and asymmetric Michael addition promoted by recyclable fluorous organocatalysts

W. Yi, Z. Zhang, X. Huang, A. Tanner, C. Cai and W. Zhang, RSC Adv., 2013, 3, 18267 DOI: 10.1039/C3RA42501K

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