Issue 22, 2013
From the journal:

RSC Advances

Ladder-like aminopropylsilsesquioxane. A nice alternative for controlled drug delivery†

Corine Tourné-Péteilh,a   Guillaume Gracy,b   Sébastien Clément,b   Jean-Marie Devoissellea  and  Ahmad Mehdi*b  

* Corresponding authors

a Institut Charles Gerhardt Montpellier UMR 5253 CNRS-UM2-ENSCM-UM1 Equipe Matériaux Avancés pour la Catalyse et la Santé UFR des Sciences Pharmaceutiques, 15 avenue Charles Flahault, 34060 Montpellier Cedex 5, France

b Institut Charles Gerhardt Montpellier, UMR 5253, Chimie Moléculaire et Organisation du Solide, Université Montpellier, Place E. Bataillon, 34095 Montpellier Cedex 5, France
E-mail: ahmad.mehdi@um2.fr

Abstract

A simple synthesis of a hybrid material with a high content (80%) of ibuprofen was reported. The drug release proceeds via a diffusion mechanism and depends on the pH. This extensive system will open new doors to introduce a large variety of drugs, with high potential for biomedical applications.

Graphical abstract: Ladder-like aminopropylsilsesquioxane. A nice alternative for controlled drug delivery

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Article information

DOI
https://doi.org/10.1039/C3RA41184B
Article type
Communication
Submitted
11 Mar 2013
Accepted
11 Apr 2013
First published
12 Apr 2013

RSC Adv., 2013,3, 8160-8163

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Ladder-like aminopropylsilsesquioxane. A nice alternative for controlled drug delivery

C. Tourné-Péteilh, G. Gracy, S. Clément, J. Devoisselle and A. Mehdi, RSC Adv., 2013, 3, 8160 DOI: 10.1039/C3RA41184B

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