Issue 22, 2013
From the journal:

RSC Advances

Simple synthesis route of mesoporous AlOOH nanofibers to enhance immune responses†

Xiupeng Wang,*a   Xia Li,*a   Yu Sogoa  and  Atsuo Itoa  

* Corresponding authors

a Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan
E-mail: xp-wang@aist.go.jp, lixia6969@hotmail.com

Abstract

A facile method to synthesize mesoporous AlOOH nanofibers using inorganic aluminum salts as the aluminum source and urea as the pore-forming and precipitating agent is reported. The uptake of AlOOH by macrophage-like cells is about 2 times of commercial Alum. The AlOOH adjuvant markedly stimulates the immune responses compared to the commercial Alum adjuvant.

Graphical abstract: Simple synthesis route of mesoporous AlOOH nanofibers to enhance immune responses

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Article information

DOI
https://doi.org/10.1039/C3RA40881G
Article type
Communication
Submitted
20 Feb 2013
Accepted
09 Apr 2013
First published
09 Apr 2013

RSC Adv., 2013,3, 8164-8167

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Simple synthesis route of mesoporous AlOOH nanofibers to enhance immune responses

X. Wang, X. Li, Y. Sogo and A. Ito, RSC Adv., 2013, 3, 8164 DOI: 10.1039/C3RA40881G

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