Issue 21, 2013

Investigation of the electrical stability of Si-nanowire biologically sensitive field-effect transistors with embedded Ag/AgCl pseudo reference electrode

Abstract

We report on the electrical stability of Si-nanowire biologically sensitive field-effect transistors (BioFETs) fabricated using conventional microfabrication technique, with an embedded Ag/AgCl pseudo-reference electrode (pRE) formed by an electrochemical method. The open-circuit potential (OCP) characteristics between the pRE and a commercial reference electrode have been measured in order to evaluate the influence of the pRE potential on the device performance. In a pH sensing mode, the fabricated pRE follows the applied potential accurately with a small offset value of below 6 mV for pH in the range of 4 to 10. The BioFET was also used for the detection of alpha fetoprotein (AFP) with a detection limit of 10 pg mL−1 and the corresponding OCP fluctuation of the pRE was less than 1.5 mV, independent of the AFP concentrations. These results suggest that the Si-NW BioFETs with the embedded Ag/AgCl pRE are very promising for reliable biosensing applications.

Graphical abstract: Investigation of the electrical stability of Si-nanowire biologically sensitive field-effect transistors with embedded Ag/AgCl pseudo reference electrode

Supplementary files

Article information

Article type
Paper
Submitted
13 Feb 2013
Accepted
15 Mar 2013
First published
15 Mar 2013

RSC Adv., 2013,3, 7963-7969

Investigation of the electrical stability of Si-nanowire biologically sensitive field-effect transistors with embedded Ag/AgCl pseudo reference electrode

T. Rim, K. Kim, N. Hong, W. Ko, C. Baek, S. Jeon, M. J. Deen, M. Meyyappan, Y. Jeong and J. Lee, RSC Adv., 2013, 3, 7963 DOI: 10.1039/C3RA40768C

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