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Issue 32, 2013
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Surface-enhanced Raman scattering microfluidic sensor

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Surface-enhanced Raman scattering (SERS) is a highly sensitive detection technique used to provide information about chemical and biological trace analytes. The confocal Raman microscope makes it possible to monitor small samples in a narrow microfluidic channel, despite the fact that the scattering intensity of the Raman signal is very weak. Recently, microfluidic chip devices coupled with on-chip SERS detection method and their applications to sensitive chemical and biological analyses have attracted significant attention. In this mini-review, highlights of advances in SERS techniques, microfluidic devices and their applications on the biological/environmental analysis of minute analytes within the recent years are provided to illustrate the impact of this rapidly growing area of research.

Graphical abstract: Surface-enhanced Raman scattering microfluidic sensor

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Publication details

The article was received on 04 Feb 2013, accepted on 12 Apr 2013 and first published on 12 Apr 2013

Article type: Review Article
DOI: 10.1039/C3RA40610E
Citation: RSC Adv., 2013,3, 13015-13026

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    Surface-enhanced Raman scattering microfluidic sensor

    Q. Li, B. Li and Y. Wang, RSC Adv., 2013, 3, 13015
    DOI: 10.1039/C3RA40610E

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