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Issue 6, 2020
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Gold-catalyzed domino reactions of alkynol and p-quinone methides: divergent synthesis of fused- and spiro-ketals

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Abstract

An efficient gold-catalyzed domino reaction of alkynyl alcohols and p-quinone methides has been successfully developed. Divergent polycyclic fused- and spiro-ketals were synthesized in good yields under mild conditions from easily available starting materials in an atom-economical manner.

Graphical abstract: Gold-catalyzed domino reactions of alkynol and p-quinone methides: divergent synthesis of fused- and spiro-ketals

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Submitted
06 Jan 2020
Accepted
16 Feb 2020
First published
19 Feb 2020

Org. Chem. Front., 2020,7, 856-861
Article type
Research Article

Gold-catalyzed domino reactions of alkynol and p-quinone methides: divergent synthesis of fused- and spiro-ketals

W. Mao, S. Lin, L. Zhang, H. Lu, J. Jia and Z. Xu, Org. Chem. Front., 2020, 7, 856
DOI: 10.1039/D0QO00022A

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