Jump to main content
Jump to site search

Issue 1, 2020
Previous Article Next Article

Ag-Catalyzed cycloisomerization of 1,6-enynamide: an intramolecular type II Alder-ene reaction

Author affiliations

Abstract

Promoted by a silver catalyst, 1,6-enynamides with a cyclic ene moiety can undergo cycloisomerization to fused N-heterobicycles. This transformation presents an unusual type II Alder-ene reaction and is believed to proceed through a catalytic cycle of formation of a keteneiminium silver intermediate, subsequent 6-endo-trig cyclization and protodemetalation.

Graphical abstract: Ag-Catalyzed cycloisomerization of 1,6-enynamide: an intramolecular type II Alder-ene reaction

Back to tab navigation

Supplementary files

Article information


Submitted
14 Oct 2019
Accepted
14 Nov 2019
First published
18 Nov 2019

Org. Chem. Front., 2020,7, 73-75
Article type
Research Article

Ag-Catalyzed cycloisomerization of 1,6-enynamide: an intramolecular type II Alder-ene reaction

M. Shen, Y. Zhang, C. Jiang, H. Xu and D. Xu, Org. Chem. Front., 2020, 7, 73
DOI: 10.1039/C9QO01258C

Social activity

Search articles by author

Spotlight

Advertisements