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Issue 9, 2019
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Facile synthesis of 2-(2-aminobenzoyl)benzoic acids via a base-promoted aerobic cascade reaction

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Abstract

A novel strategy for the regiospecific synthesis of 2-(2-aminobenzoyl)benzoic acids via a base-promoted aerobic cascade reaction has been exploited. The protocol led to a wide panel of 2-(2-aminobenzoyl)benzoic acids with a broad substrate scope in an atom-economical manner. Six new bonds were sequentially formed in this one-pot procedure.

Graphical abstract: Facile synthesis of 2-(2-aminobenzoyl)benzoic acids via a base-promoted aerobic cascade reaction

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Article information


Submitted
23 Jan 2019
Accepted
04 Mar 2019
First published
05 Mar 2019

Org. Chem. Front., 2019,6, 1383-1386
Article type
Research Article

Facile synthesis of 2-(2-aminobenzoyl)benzoic acids via a base-promoted aerobic cascade reaction

J. Shen, Y. Chen, T. Chen, Z. Zou, Y. Feng and Q. You, Org. Chem. Front., 2019, 6, 1383
DOI: 10.1039/C9QO00101H

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