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Issue 12, 2016
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Self-healing hydrogels triggered by amino acids

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Abstract

Nine amino acids with different chemical properties have been chosen to promote the formation of hydrogels based on the bolamphiphilic gelator A: three basic amino acids (arginine, histidine and lysine), one acidic amino acid (aspartic acid), two neutral aliphatic amino acids (alanine and serine) and three neutral aromatic amino acids (phenylalanine, tyrosine and tryptophan). Although hydrogels are obtained under any conditions, strong and thermoreversible hydrogels are formed by the addition of Arg to the bolamphiphilic gelator. These hydrogels have physiological pH and self-healing properties and may be used for regenerative medicine applications.

Graphical abstract: Self-healing hydrogels triggered by amino acids

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Supplementary files

Article information


Submitted
20 Aug 2016
Accepted
27 Sep 2016
First published
28 Sep 2016

Org. Chem. Front., 2016,3, 1699-1704
Article type
Research Article

Self-healing hydrogels triggered by amino acids

N. Zanna, A. Merlettini and C. Tomasini, Org. Chem. Front., 2016, 3, 1699 DOI: 10.1039/C6QO00476H

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