Issue 1, 2016

Copper-catalyzed domino synthesis of benzo[b]thiophene/imidazo[1,2-a]pyridines by sequential Ullmann-type coupling and intramolecular C(sp2)–H thiolation

Abstract

The copper-catalyzed double C–S bond formation via Ullmann-type S-arylation and C–H thiolation using K2S as a sulfur source is described. This novel one-step sulfur-incorporation method provides a straightforward avenue to benzo[b]thiophene and imidazo[1,2-a]pyridine frameworks.

Graphical abstract: Copper-catalyzed domino synthesis of benzo[b]thiophene/imidazo[1,2-a]pyridines by sequential Ullmann-type coupling and intramolecular C(sp2)–H thiolation

Supplementary files

Article information

Article type
Research Article
Submitted
10 Oct 2015
Accepted
14 Nov 2015
First published
17 Nov 2015

Org. Chem. Front., 2016,3, 66-70

Author version available

Copper-catalyzed domino synthesis of benzo[b]thiophene/imidazo[1,2-a]pyridines by sequential Ullmann-type coupling and intramolecular C(sp2)–H thiolation

K. Yan, D. Yang, W. Wei, S. Lu, G. Li, C. Zhao, Q. Zhang and H. Wang, Org. Chem. Front., 2016, 3, 66 DOI: 10.1039/C5QO00311C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements