Jump to main content
Jump to site search

Issue 4, 2015
Previous Article Next Article

Cationic iridium-catalyzed C–H alkylation of 2-substituted pyridine N-oxides with acrylates

Author affiliations

Abstract

The reaction of 2-arylmethyl-, 2-aryl-, and 2-alkyl substituted pyridine N-oxides with acrylates proceeded in the presence of a cationic Ir-rac-BINAP catalyst under heating conditions. Various 2,6-disubstituted pyridine N-oxides were obtained by C–H alkylation at the C6-position.

Graphical abstract: Cationic iridium-catalyzed C–H alkylation of 2-substituted pyridine N-oxides with acrylates

Back to tab navigation

Supplementary files

Publication details

The article was received on 30 Dec 2014, accepted on 09 Feb 2015 and first published on 11 Feb 2015


Article type: Research Article
DOI: 10.1039/C4QO00355A
Author version
available:
Download author version (PDF)
Citation: Org. Chem. Front., 2015,2, 383-387

  •   Request permissions

    Cationic iridium-catalyzed C–H alkylation of 2-substituted pyridine N-oxides with acrylates

    T. Shibata and H. Takano, Org. Chem. Front., 2015, 2, 383
    DOI: 10.1039/C4QO00355A

Search articles by author

Spotlight

Advertisements