Issue 41, 2016
From the journal:

Polymer Chemistry

Glyconanoparticles with controlled morphologies and their interactions with a dendritic cell lectin†

Gokhan Yilmaz,abc   Lea Messager,d   Anne S. Gleinich,e   Daniel A. Mitchell,e   Giuseppe Battaglia*d  and  C. Remzi Becer ORCID logo *c  

* Corresponding authors

a Department of Chemistry, University of Warwick, Coventry, UK

b Department of Basic Sciences, Turkish Military Academy, Ankara, Turkey

c Polymer Chemistry Laboratory, School of Engineering and Materials Science, Queen Mary, University of London, London, UK
E-mail: r.becer@qmul.ac.uk

d Department of Chemistry, University College London, London, UK

e Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, Coventry, UK

Abstract

Well-defined amphiphilic block glycopolymers with equal mannose content have been self-assembled in aqueous solution to form glyconanoparticles with different morphologies. The size and shape of nanoparticles have significant effects on the interactions with the dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN; CD209), characterized using a surface plasmon resonance spectrometer (SPR).

Graphical abstract: Glyconanoparticles with controlled morphologies and their interactions with a dendritic cell lectin

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Article information

DOI
https://doi.org/10.1039/C6PY01523A
Article type
Communication
Submitted
30 Aug 2016
Accepted
30 Sep 2016
First published
30 Sep 2016
This article is Open Access
Creative Commons BY-NC license

Polym. Chem., 2016,7, 6293-6296

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Glyconanoparticles with controlled morphologies and their interactions with a dendritic cell lectin

G. Yilmaz, L. Messager, A. S. Gleinich, D. A. Mitchell, G. Battaglia and C. R. Becer, Polym. Chem., 2016, 7, 6293 DOI: 10.1039/C6PY01523A

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