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Issue 36, 2016
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Injectable cationic hydrogels with high antibacterial activity and low toxicity

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Abstract

Antibacterial materials have always suffered from high toxicity. In this study, we fabricated injectable and biodegradable hydrogels utilizing poly(hexamethylene guanidine) hydrochloride and poly(ethylene glycol) as the backbone through a thiol–ene “click” reaction under physiological conditions, and they showed remarkably low toxicity and high and broad-spectrum antibacterial activity.

Graphical abstract: Injectable cationic hydrogels with high antibacterial activity and low toxicity

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Supplementary files

Article information


Submitted
02 Aug 2016
Accepted
02 Aug 2016
First published
17 Aug 2016

Polym. Chem., 2016,7, 5620-5624
Article type
Communication

Injectable cationic hydrogels with high antibacterial activity and low toxicity

H. Du, Y. Wang, X. Yao, Q. Luo, W. Zhu, X. Li and Z. Shen, Polym. Chem., 2016, 7, 5620
DOI: 10.1039/C6PY01346E

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