Issue 32, 2015
From the journal:

Polymer Chemistry

Engineering thermoresponsive polyether-based nanogels for temperature dependent skin penetration†

M. Asadian-Birjand,a   J. Bergueiro,a   F. Rancan,b   J. C. Cuggino,a   R.-C. Mutihac,a   K. Achazi,a   J. Dernedde,c   U. Blume-Peytayi,b   A. Vogtb  and  M. Calderón*a  

* Corresponding authors

a Institut für Chemie und Biochemie, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany
E-mail: marcelo.calderon@fu-berlin.de
Fax: +49-30-838-459368

b Clinical Research Center of Hair and Skin Science, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany

c Charité – Universitätsmedizin Berlin, Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, CVK, Augustenburger Platz 1, 13353 Berlin, Germany

Abstract

Highly biocompatible thermoresponsive nanogels (tNGs) based on oligo ethylene glycol (OEG) as thermoresponsive unit and dendritic polyglycerol (dPG) as cross-linker, were precisely engineered in terms of size and volume phase transition temperature (VPTT). Preliminary uptake studies into human skin were realized to show the temperature-dependent internalization behavior of these systems.

Graphical abstract: Engineering thermoresponsive polyether-based nanogels for temperature dependent skin penetration

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Article information

DOI
https://doi.org/10.1039/C5PY00924C
Article type
Communication
Submitted
15 Jun 2015
Accepted
15 Jun 2015
First published
16 Jun 2015
This article is Open Access
Creative Commons BY-NC license

Polym. Chem., 2015,6, 5827-5831

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Engineering thermoresponsive polyether-based nanogels for temperature dependent skin penetration

M. Asadian-Birjand, J. Bergueiro, F. Rancan, J. C. Cuggino, R.-C. Mutihac, K. Achazi, J. Dernedde, U. Blume-Peytayi, A. Vogt and M. Calderón, Polym. Chem., 2015, 6, 5827 DOI: 10.1039/C5PY00924C

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