Issue 9, 2015

Glycopolymer-based nanoparticles: synthesis and application

Abstract

Synthetic glycopolymers with pendent sugar moieties are able to interact with lectins as multivalent ligands in a similar manner to natural glycoproteins. Nanoparticles (NPs), due to their small size and high surface/volume ratio, lead to very different properties compared with bulk-matter, and NPs have shown great potential in nanomedicine and other biological applications. NPs with glycopolymers on the surface are one of the desirable bio-active particles and an important material to investigate. This review focuses on the synthesis of various glycopolymer-based nanoparticles via different approaches such as self-assembly and the preparation of glycopolymer-conjugated inorganic NPs, and their different applications.

Graphical abstract: Glycopolymer-based nanoparticles: synthesis and application

Article information

Article type
Review Article
Submitted
15 Dec 2014
Accepted
17 Jan 2015
First published
19 Jan 2015

Polym. Chem., 2015,6, 1417-1430

Author version available

Glycopolymer-based nanoparticles: synthesis and application

X. Li and G. Chen, Polym. Chem., 2015, 6, 1417 DOI: 10.1039/C4PY01740D

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