Macromolecular ruthenium complexes as anti-cancer agents†
Abstract
Ruthenium complexes have shown promise as anti-cancer therapeutics. Among them, RAPTA-C [RuCl2(p-cymene)(PTA)] with the water-soluble 1,3,5-triaza-7-phosphaadamantane (PTA)
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* Corresponding authors
a
Centre for Advanced Macromolecular Design, University of New South Wales, Sydney, NSW 2052, Australia
E-mail:
M.Stenzel@unsw.edu.au
Fax: +61-2-93856250
Tel: +61-2-93854344
b Cooperative Research Centre (CRC) for Polymers, 8 Redwood Drive, Notting Hill, Victoria 3168, Australia
c NMR Facility, Mark Wainwright Analytical Centre, University of New South Wales, Sydney, NSW 2052, Australia
Ruthenium complexes have shown promise as anti-cancer therapeutics. Among them, RAPTA-C [RuCl2(p-cymene)(PTA)] with the water-soluble 1,3,5-triaza-7-phosphaadamantane (PTA)
B. M. Blunden, D. S. Thomas and M. H. Stenzel, Polym. Chem., 2012, 3, 2964 DOI: 10.1039/C2PY20439H
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