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Issue 7, 2011
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Polymersomes enhance the immunogenicity of influenza subunit vaccine

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Abstract

In this study poly(γ-benzyl-L-glutamate)-K (PBLG50-K) polymersomes are tested as an immune adjuvant for an antigen, influenza hemagglutinin (HA). The polymersomes were prepared according to a solvent removal method and loaded with HA antigensvia adsorption. The immunogenicity of the resulting hybrid assemblies was tested in vivo, resulting in an improvement of the immune response for the influenza antigen co-administered with the polymersomes.

Graphical abstract: Polymersomes enhance the immunogenicity of influenza subunit vaccine

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Article information


Submitted
11 Jan 2011
Accepted
03 Mar 2011
First published
29 Mar 2011

Polym. Chem., 2011,2, 1482-1485
Article type
Communication

Polymersomes enhance the immunogenicity of influenza subunit vaccine

C. Barnier Quer, H. Robson Marsden, S. Romeijn, H. Zope, A. Kros and W. Jiskoot, Polym. Chem., 2011, 2, 1482
DOI: 10.1039/C1PY00010A

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