Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 3, 2002
Previous Article Next Article

The pH dependence of the anisotropy factors of essential amino acids

Author affiliations

Abstract

In order to examine the pH dependence of the anisotropy factor (g) of all the essential amino acids, at pHs 1, 2, 7 and 11, the molar absorption coefficient (ε) and circular dichroism (Δε) were determined in aqueous solution. The g factors were high, and except for Asn and the aromatic and sulfur-containing compounds (Tyr, His, Trp, Cys and Met) the gmax values are larger than 0.01 in the pH range 1–7. Large g factors of aliphatic amino acids are observed even at pH 11. On the whole the magnitudes of the g factors at pH 1 are 2–3 times those at pH 7. The n,π* transition of the carboxylic group is the major contributor to the large g factors in amino acids such as Ala and Val. It is thought that in connection with the possible origin of amino acid homochirality generated by circularly polarised light irradiation, the % ee (≡ % op) of the amino acid generated will also be pH dependent in a manner similar to that previously reported for Leu.

Graphical abstract: The pH dependence of the anisotropy factors of essential amino acids

Back to tab navigation

Supplementary files

Article information


Submitted
20 Sep 2001
Accepted
05 Dec 2001
First published
18 Jan 2002

J. Chem. Soc., Perkin Trans. 2, 2002, 582-590
Article type
Paper

The pH dependence of the anisotropy factors of essential amino acids

H. Nishino, A. Kosaka, G. A. Hembury, K. Matsushima and Y. Inoue, J. Chem. Soc., Perkin Trans. 2, 2002, 582
DOI: 10.1039/B108575C

Search articles by author

Spotlight

Advertisements