Pigments of fungi. Part 49.1 Structure and biosynthesis of dermocanarin 4, a naphthoquinone-dihydroanthracenone dimer from the fungus Cortinarius sinapicolor Cleland

Abstract

Dermocanarin 4 3, a novel naphthoquinone-dihydroanthracenone dimer containing a nine membered lactone ring has been isolated from the fruit bodies of the Australasian fungus Cortinarius sinapicolor and the structure and axial stereochemistry have been determined by spectroscopic methods. The biosynthesis of dermocanarin 4 has been studied in intact toadstools by feeding experiments involving [Me-¹³C]methionine, sodium [2-¹³C]acetate and sodium [1,2-¹³C₂]acetate.