An improved procedure for the synthesis of substituted acetylenes from the reaction of acetylene gas with aryl iodides under palladium–copper catalysis

Abstract

Dimethylformamide facilitated the palladium–copper catalysed reaction of acetylene gas with aryl iodides in a closed system to give disubstituted acetylenes in fair to excellent yields. Use of chloroform as solvent gave mixtures of mono- and di-substituted acetylenes.