Stereoselective C-3 substitution of 1,5-anhydro-2-deoxy-2-formyl-3,4,6-tri-O-methylhex-1-enitols: entry to ribo and xylo series
Abstract
Reaction of 1,5-anhydro-2-deoxy-2-formyl-3,4,6-tri-O-methyl-D-lyxo-hex-1-enitol 1 and its arabino epimer 3 with various nucleophiles under Lewis acid catalysis led to stereoselective C-3 substitution.