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Issue 24, 1992
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Synthesis of some stable ozonides with anti-malarial activity

Abstract

We describe the synthesis of variously substituted 8,9,10,11-tetraoxatricyclo[5.2.1.12,6]undecan-4-ones. Several of these stable ozonides exhibited activity (IC50′s of 10–20 µg cm–3) against a chloroquine-resistant strain of the malaria parasite Plasmodium falciparum.

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Article information


J. Chem. Soc., Perkin Trans. 1, 1992, 3251-3252
Article type
Paper

Synthesis of some stable ozonides with anti-malarial activity

L. de Almeida Barbosa, D. Cutler, J. Mann, G. C. Kirby and D. C. Warhurst, J. Chem. Soc., Perkin Trans. 1, 1992, 3251
DOI: 10.1039/P19920003251

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