Issue 5, 1991

New synthetic route to N,N′-diaminohydantoins from hydrazido pyridinium salts

Abstract

α-Bromoarylacetohydrazides were converted by pyridine into the corresponding arylacetylhydrazinopyridinium salts. Treated with triethylamine, these pyridinium salts afford 4-aryl-1,3-diaminohydantoins. The study of the mechanism of this unexpected reaction lead us to extend its scope to 4-arylhydantoins bearing two different substituted amino groups on nitrogens 1 and 3.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1991, 1143-1146

New synthetic route to N,N′-diaminohydantoins from hydrazido pyridinium salts

C. Florac, P. Le Grel, M. Baudy-Floc'h and A. Robert, J. Chem. Soc., Perkin Trans. 1, 1991, 1143 DOI: 10.1039/P19910001143

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