Structure and spectral properties of β-carbolines. Part 3. Synthesis and stereochemistry of 1,2,3,4,6,7,9,10,15b,15c-decahydropyrido[1″,2″:1′,2′]pyrazino[4′,3′:1,2]pyrido[3,4-b]indoles

Abstract

Diastereoisomers of a new heterocyclic system, i.e. 1,2,3,4,6,7,9,10,15b,15c-decahydropyrido-[1″,2″:1′,2′]pyrazino[4′,3′:1,2]pyrido[3,4-b]indoles (7a) and (7b), as well as their 6- and 7-oxo derivatives (5a),(5b) and (2a),(2b), respectively, were synthesized. The structure of individual diastereoisomers was determined using ¹H and ¹³C NMR techniques.