The preparation of 2,3,3a,4,5,6-hexahydro-8-methoxy-1H-phenalene

Abstract

The previously unknown methoxy substituted benzene derivative 2,3,3a,4,5,6-hexahydro-8-methoxy-1H-phenalene (3a) has been prepared by two routes. One starts from 6-methoxy-α-tetralone (4a) and involves a single 3-carbon extension and cyclization of the alcohol (7b); the other starts from 3-(3-methoxyphenyl)propanoic acid (5a) and proceeds via a 4-carbon extension and a double cyclization of the diol (10).