SCHEDULED MAINTENANCE
The thromboxane A1(TXA1) analogue (1), which retains the characteristic bridge oxygen atom of the TXA molecule, has been synthesized from the bicyclic ketone (2). Stereochemical control of alkylation of the bicyclic ketone (2) was achieved by the use of enamines.
M. F. Ansell, J. S. Mason and M. P. L. Caton, J. Chem. Soc., Perkin Trans. 1, 1984, 1061 DOI: 10.1039/P19840001061
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