The synthesis of the 9,11-hydroxyethano-prostaglandin endoperoxide H2 analogue
Abstract
The 9,11-hydroxyethano-prostaglandin endoperoxide H2 analogue (4a) and its methyl ester (4b) have been prepared in 4.3 and 10% yield respectively from the readily prepared 3-exo-methoxycarbonyl-6-endo-hydroxy-5-exo-iodonorborn-2-endo-ylacetic acid δ-lactone (5).