Heating Diels–Alder adducts of steroidal-5,7-dienes and 4-phenyl-1,2,4-triazoline-3,5-dione with mineral base in an appropriate solvent at 120 °C gives the corresponding steroidal-5,7-dienes in high yields. This method is applied to a synthesis of 22,23-epoxyergosterols. The irradiation of this compound followed by thermal isomerization gives 22,23-epoxyvitamin D2.
M. Tada and A. Oikawa, J. Chem. Soc., Perkin Trans. 1, 1979, 1858 DOI: 10.1039/P19790001858
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...