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Issue 7, 1977
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Synthesis of C-nucleosides. Part 14. 5(3)-Glycosyl-1,2,4-triazole-3(5) carboxamides as analogues of ribavirin

Abstract

Alkyl thioimidates react with hydrazides of methyl hydrogen oxalate and oxamic acid to yield methyl 1,2,4-triazole 3(5)-carboxylates and -carboxamides. Ribo-, deoxyribo- and arabino-C-nucleoside analogues of ribavirin have been prepared and their structures established by n.m.r. and mass spectrometry.

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Article information


J. Chem. Soc., Perkin Trans. 1, 1977, 761-764
Article type
Paper

Synthesis of C-nucleosides. Part 14. 5(3)-Glycosyl-1,2,4-triazole-3(5) carboxamides as analogues of ribavirin

T. Huynh-Dinh, J. Igolen, E. Bisagni, J. P. Marquet and A. Civier, J. Chem. Soc., Perkin Trans. 1, 1977, 761
DOI: 10.1039/P19770000761

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