Unconventional nucleotide analogues. Part XIII. (2S,4S)-2-hydroxymethyl- and 2-carboxy-4-(purin-9-yl)pyrrolidines
Abstract
The synthesis of (4S)-4-adeninyl, 4-guaninyl, and 4-hypoxanthinyl derivatives of L-proline and L-prolinol is described. Adeninyl- and hypoxanthinyl-prolinols inhibit the growth of BHK cells.