Jump to main content
Jump to site search

Issue 0, 1973
Previous Article Next Article

Naphtho[1,2-b]thiophen. Part I. Preparation and electrophilic substitution

Abstract

Naphtho[1,2-b]thiophen was prepared from 3,4-dihydronaphthalen-1 (2H)-one by a five-stage process. Bromination, formylation, acetylation, and lithiation of naphtho[1,2-b] thiophen occurred at the 2-position. Nitration gave a mixture of the 2- and 5-nitro-derivatives; the structure of the latter was confirmed by transforming it into the 5-bromo-compound, which could be prepared unambiguously. Bromination and nitration of ethyl naphtho[1,2-b]thiophen-2-carboxylate gave mainly the 5-substituted compound in each case.

Back to tab navigation

Article information


J. Chem. Soc., Perkin Trans. 1, 1973, 2956-2960
Article type
Paper

Naphtho[1,2-b]thiophen. Part I. Preparation and electrophilic substitution

K. Clarke, D. N. Gregory and R. M. Scrowston, J. Chem. Soc., Perkin Trans. 1, 1973, 2956
DOI: 10.1039/P19730002956

Search articles by author

Spotlight

Advertisements