Issue 0, 1973

A convenient method for the synthesis of baicalein (5,6,7-trihydroxyflavone) and 4′-methylgamatin (4-methoxy-3-methyl-7-phenylfuro-[3,2-g][1]benzopyran-5-one)

Abstract

We report a modified synthesis of baicalein by Dakin oxidation of 6-acetyl-5,7-dihydroxyflavone (I)(obtained by condensation of phloroacetophenone with ethyl benzoylacetate), and the elaboration of a furan ring on structure (I) by a conventional method to give 4′-methylgamatin.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1973, 503-505

A convenient method for the synthesis of baicalein (5,6,7-trihydroxyflavone) and 4′-methylgamatin (4-methoxy-3-methyl-7-phenylfuro-[3,2-g][1]benzopyran-5-one)

Y. S. Agasimundin and S. Siddappa, J. Chem. Soc., Perkin Trans. 1, 1973, 503 DOI: 10.1039/P19730000503

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