Issue 0, 1972

Steroid amines. Part V. 20-Pyrrolidin-1-ylpregnane derivatives

Abstract

The Leuckart reaction with pyrrolidine has been applied to 3β-hydroxypregn-5-en-20-one and to 3β-hydroxy-5α-pregnan-20-one. Mixtures of (20S)-20-pyrrolidin-1-yl-17β-pregnanes and 20ξ-pyrrolidin-1-yl-17α-pregnanes were obtained; the expected (20R)-20-pyrrolidin-1-yl-17β-pregnanes were not isolated.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1972, 1420-1424

Steroid amines. Part V. 20-Pyrrolidin-1-ylpregnane derivatives

M. Davis, E. W. Parnell and J. Rosenbaum, J. Chem. Soc., Perkin Trans. 1, 1972, 1420 DOI: 10.1039/P19720001420

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