Jump to main content
Jump to site search

Issue 37, 2019
Previous Article Next Article

Facile synthesis of stable selenocystine peptides and their solution state NMR studies

Author affiliations

Abstract

A facile general route for the synthesis of various selenocystine tripeptides containing acidic, basic and neutral side chain amino acids is reported. Here, TFA labile side chain protected selenocysteine has been used as a precursor for the synthesis of selenopeptides. The peptides are highly stable in dimethyl sulphoxide, thus enabling detailed NMR studies by solution phase 1- and 2-dimensional NMR spectroscopy.

Graphical abstract: Facile synthesis of stable selenocystine peptides and their solution state NMR studies

Back to tab navigation

Supplementary files

Article information


Submitted
31 Aug 2019
Accepted
03 Sep 2019
First published
05 Sep 2019

Org. Biomol. Chem., 2019,17, 8533-8536
Article type
Communication

Facile synthesis of stable selenocystine peptides and their solution state NMR studies

R. P. Gokula, K. Patel, S. K. Maurya and H. B. Singh, Org. Biomol. Chem., 2019, 17, 8533
DOI: 10.1039/C9OB01910C

Social activity

Search articles by author

Spotlight

Advertisements