Recent advances in metal-free aerobic C–H activation
Herein we describe recent developments in selective, metal-free, dioxygen-induced C–H activation. This method of activating C–H bonds is an attractive alternative to traditional methodologies as it uses dioxygen, an inherently sustainable and widely accessible oxidant, in place of expensive or toxic metals and/or hazardous peroxides. Reactions developed on the basis of using aerobic C–H activation are also discussed.
- This article is part of the themed collections: Direct C-H Functionalization in Method Development and Late Stage Functionalization and Synthetic methodology in OBC