Issue 46, 2018

Electrochemical cobalt-catalyzed C–H or N–H oxidation: a facile route to synthesis of substituted oxindoles

Abstract

Two comparable protocols for the electrochemical cobalt-catalyzed C–H/N–H oxidation have been exploited for the synthesis of substituted oxindoles via radical pathways. The electrochemical cobalt-catalyzed system was demonstrated to be efficient and eco-friendly and avoided the use of stoichiometric oxidants to afford the arylation or alkylation products in good yields at room temperature.

Graphical abstract: Electrochemical cobalt-catalyzed C–H or N–H oxidation: a facile route to synthesis of substituted oxindoles

Supplementary files

Article information

Article type
Communication
Submitted
06 Oct 2018
Accepted
01 Nov 2018
First published
01 Nov 2018

Org. Biomol. Chem., 2018,16, 8917-8921

Electrochemical cobalt-catalyzed C–H or N–H oxidation: a facile route to synthesis of substituted oxindoles

Y. Yu, P. Zheng, Y. Wu and X. Ye, Org. Biomol. Chem., 2018, 16, 8917 DOI: 10.1039/C8OB02485E

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