An alternative route for the synthesis of hydroxylated pillararene-based amphiphiles†
Conformational mobilities of the units and host–guest complexation with n-octyltrimethylammonium hexafluorophosphate of the synthesized perbenzylated pillararenes were studied. The formed complex was confirmed by proton nuclear magnetic resonance spectroscopy and mass spectral analysis. Hydroxylated pillararene-based amphiphiles were synthesized by a co-cyclization strategy followed by catalytic hydrogenation. This approach unlocks the synthesis and the design of a wide range of structural manipulations to these amphiphilic pillararenes.
- This article is part of the themed collection: Supramolecular chemistry in OBC