E-Selective synthesis of vinyl sulfones via silver-catalyzed sulfonylation of styrenes†
An efficient and highly E-selective protocol for the synthesis of vinyl sulfones is described. This simple protocol demonstrates the first synthesis of vinyl sulfones via a silver-catalyzed C–S bond coupling reaction. In addition, the success of the reaction was found to be critically dependent on the use of TEMPO as the additive.
- This article is part of the themed collection: Synthetic methodology in OBC